The study found that 40 percent of patients with all had deletions or mutations in one of three so - called " master genes " that control the normal differentiation of immature progenitor cells into mature b lymphocytes 研究发现all患者中有40至少有一个“主基因”发生了缺失或突变，这三个“主基因”控制未成熟的祖细胞正常分化为成熟的b淋巴细胞。
